Colorectal cancer (CRC) is a type of cancer that affects the colon, rectum and appendix, caused by the appearance of a malignant abnormal tissue mass (neoplasm). It is the third cancer with the highest mortality rate and the fourth cancer type with the highest incidence in the world, being more frequent in men than in women.
This type of cancer is caused by the uncontrolled growth of cells that are part of the epithelium of the large intestine, evolving into a malignant tumor (carcinoma) that spreads in the walls of the colon or rectum and can extend to other tissues and organs of the body (causing metastasis).
Risk factors may include:
Age: people between 60 and 70 years old
Presence of adenomatous polyps
Previous cancer diagnoses
Hereditary factors (family history of colorectal cancer).
Unhealthy eating habits, alcohol consumption, smoking and low physical activity.
Diseases such as ulcerative colitis and Crohn's disease
Change in bowel function, including diarrhea or constipation or a change in stool consistency.
Rectal bleeding or blood in the stool.
Persistent abdominal discomfort, such as cramping, gas, or pain.
Feeling of heaviness in the bowel
Weakness or fatigue
Unexplained weight loss
The treatment of colorectal cancer may include: surgery, intravenous or oral chemotherapy or medications, intrathecal chemotherapy, radiotherapy, use of colon stents and medications to prevent and treat nausea or vomiting due to the treatment, being a very aggressive and exhaustive process for the patient.
Therefore, the search for drugs or therapies that can help patients find relief and improvement in their quality of life are essential to ensure the health and welfare of patients suffering from this cancer being possible through the development of clinical trials that allow research and study of this type of cancer to find a treatment aimed at curing this disease.
At Alpha Research you can find an opportunity to contribute to clinical research and save the lives of many people by volunteering in our studies. Apply and receive the best medical care with a team of specialists and trained professionals.
Therefore, if you meet the following criteria, participate in our trial:
We are looking for men and women between 18 and 80 years old.
Confirmed diagnosis of colorectal adenocarcinoma
ECOG (patient's disease progression) scale of 0-1
Failure of previous chemotherapy treatments
Adequate hematologic and organ function
Pregnant and lactating women are not eligible to participate